Preconception genetic test
for couples planning a baby

UP TO 5 OUT OF 100 COUPLES ARE AT RISK OF HAVING A CHILD WITH A SERIOUS MONOGENIC DISEASE.

ELIMINATE THE RISK BY SCREENING YOUR GENES WITH THE PANDA TEST.

PANDA test

4 weeks

BLOOD COLLECTION

BLOOD COLLECTION POINT

DNA ISOLATION AND TESTING

LABORATORY

COMPARISON OF MUTATED GENES

LABORATORY

RESULTS

PANDA WILL FIND OUT IF YOU AND YOUR PARTNER ARE RISK OF GENETIC ABNORMALITIES IN YOUR BABY

BLOOD COLLECTION POINT

CONSULTATION WITH A CLINICAL GENETICIST

BLOOD COLLECTION POINT

Why test ourselves?

EVEN THOUGH BOTH PARTNERS ARE APPARENTLY HEALTHY, THEY MAY BE CARRIERS OF A HEREDITARY DISEASE.

Each of us is a carrier of about 2-10 monogenic genetic diseases. Some of these predispositions do not affect life, but others may cause serious diseases such as cystic fibrosis or spinal muscular atrophy.

If I am just a carrier, then I will not develop the disease, but if I plan a family with another such carrier, there is a 25% risk of having an offspring with a serious genetic disease.

Unfortunately, most partners find out about their genetic burden after the birth of the affected offspring.

The PANDA test helps to detect such risk in advance.

Avoid this risk by getting tested.

I want to examine my genes

Each person has two copies of the same gene. One is inherited from the mother and one from the father. For hidden ( also known as recessive) genetic diseases, if we inherit the mutation from only one parent, we still have a second copy that is healthy. In this case, we are so-called healthy carriers. But the problem arises when the two mutated copies of the same gene are brought together.

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What is the price of the PANDA test?

For the purposes of the PANDA genetic test, your DNA is obtained from your blood and examined. The result reveals whether you and your partner are genetically and reproductively compatible. That is, whether your future offspring may be at risk of a genetic disease.

Individuals can also undergo the test.

We offer three types of tests:

PANDA Infertility, PANDA Carrier and PANDA Exom.

kolik stoji

Each year about 1-2% of babies in Europe are born with a serious genetic condition that can be prevented by the PANDA test.

About 1 in every 30 people is a carrier of spinal muscular atrophy.

PANDA Infertility

PANDA Carrier

PANDA Exom

€400

A primary genetic test performed before a couple is trying to conceive. The test is tailored to patients with fertility issues. However, it can also be used if trying to conceive spontaneously. PANDA Infertility provides diagnosis for the 4 most common rare disorders in our population.

These are:

● cystic fibrosis

● spinal muscular atrophy,

● non-syndromic deafness

● Fragile X syndrome

The test also examines variants of:

● infertility causes and their treatment,

● genetic causes of infertility or embryonic developmental disorders

● thrombophilic mutations

€600

Extended genetic testing of a couple offered before conception. The PANDA Carrier provides diagnostic testing of 110 most common monogenic recessive diseases. In addition to cystic fibrosis, spinal muscular atrophy, Fragile X syndrome and deafness, it also focuses on inborn errors of metabolism, such as phenylketonuria, visual and hearing impairment, and musculoskeletal and skin diseases. The examination is designed to minimize the risk of having an offspring with a monogenic disease.
According to the recommendations of the American College of Medical Genetics (ACMG), a test of such a scope should be offered to all pregnant women and couples planning to conceive.

€1200

The largest scope of testing that can be provided in the framework of testing for hidden (recessive) mutations in a couple. The test screens for almost all diseases with a known genetic cause and maximally reduces the risk

of monogenic disease in offspring.

NOT SURE WHICH PANDA TO CHOOSE? FILL OUT OUR FORM AND WE WILL HELP YOU DECIDE WHICH ONE IS RIGHT FOR YOU.

seznam

Here is the list of the 110 most common monogenic recessive diseases that we test in our laboratory.

JAK PROBÍHA

ONE BLOOD COLLECTION = MANY ANSWERS.

All that is needed to perform the test is a blood collection.

We isolate DNA from the blood sample in the laboratory, which is afterwards analysed by experts in our molecular genetics’ laboratory. Finally, the data is bioinformatically processed.

The test results in a comparison of your mutated genes and a determination of the gene compatibility of the couple, providing important information about the health of your future offspring.

Your PANDA results, along with a description of the mutations found in your genes, will be provided to you within 4 weeks of blood collection. You may need a consultation with a clinical geneticist to discuss any variants found and the possible risks.
If there is anything that is not clear to you during the consultation, the clinical geneticist will explain everything and suggest a further course of action.

How does PANDA work?

What will PANDA reveal?

The testing has not shown any mutual risks for me and my partner.

Well done. None of the mutations you have were found are in the same gene, so there is no risk of having an offspring with any of the genetic diseases tested for.

The test showed that both my partner and I are carriers of the same disease. Do we still have a chance of having a healthy baby?

Yes, you do. Even if the test reveals that you and your partner carry the mutation in the same gene, there is a good chance of a healthy baby. You can benefit from the method of preimplantation genetic testing of embryos. This test is a part of assisted reproduction methods and allows you to select an embryo without genetic burden. Only embryos without mutated genes will be transferred into the mother's womb, thus preventing the transmission of disease to the offspring.

I took the test alone some time ago, but now my partner and I are planning a family. What should I do?

If you have not been identified as a carrier, examination of your partner is not necessary. If any mutation has been found, your partner may also need to be tested before you start rying for a baby. We are able to evaluate the compatibility of the couple retrospectively. It will be the same as if you came together.

CO PROZRADÍ

Who gave life to PANDA?

AIN’T NO PANDA LIKE OUR PANDA

The PANDA Infertility test, originally developed in 2018 at the Repromeda Infertility Clinic, has completely replaced the preconception genetic diagnosis methods used in the past. Since its introduction, more than 8,000 patients have undergone the test.

With development of the PANDA Infertility Panel, our research certainly didn't end there; in 2021, we began testing with a new, expanded version of the PANDA Carrier. Testing with the PANDA Carrier can reduce the risk of having a genetically affected child by 10 to 20 times.

In 2022, we expanded our testing portfolio with the most comprehensive test, PANDA Exom. The test screens for almost all diseases with a known genetic cause and reduces the risk of offspring being born with a monogenic disease to a maximum extent.

KDO